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Animal Facility

Animal house is designed to perform experiments in conditions of GLP (Good Laboratory Practice). Animal house consists of two main parts: experimental laboratories and an area were animals are breaded. Additionally there are some technical areas e.g. quarantine rooms, repositories, and social rooms. The clean part on animal house is protected by highly specialized systems of autoclaves, air showers and windows allowing safe transfers on animals, cages and food between particular areas. In animal house about five thousands of mice in IVC system and about six thousands of mice in conventional cages, rats (about three thousands in IVC system) and rabbits may be kept at the same time including very sensitive immunodeficient strains of these animals commonly used in some specialized studies including transplantation and cancer research.
In experimental part well equipped surgery rooms are available. In this area several advanced instruments are localized. They include the computer tomography (Argus CT, Sedecal), in vivo visualization system (either fluorescence or luminescence readout – PhotonImager Optima Basic, Biospace Lab), X-ray machine (RS 2000 X-R ay Biological Irradiator, RadSource) and equipment for behavioral experiments (IntelliCage by New Behavior and ActiMot2 System, TSE Systems). In other part of animal house there are three specialized laboratories. First is hematological and biochemical laboratory in which basic analyses of blood and urine components could be carried out. It is equipped also with two modern chromatographs working in both gas (GC – 2010 Plus, Shimadzu) and high performance liquid chromatography formats (HPLC Prominence, Shimadzu). Further, the histological laboratory equipped with several advanced machines allowing automatic processing of histological samples is located. Here the high quality microscope is installed as well. Third laboratory is equipped with the cell culture instrumentation including the CO2 incubator, sterile hood and inverted microscope. All analytical fields of animal house may be supported by very well equipped laboratories localized in biotechnology wing of WCAT. Animal house is designed to perform experiments in conditions of GLP (Good Laboratory Practice). Animal house consists of two main parts: experimental laboratories and an area were animals are breaded. Additionally there are some technical areas e.g. quarantine rooms, repositories, and social rooms. The clean part on animal house is protected by highly specialized systems of autoclaves, air showers and windows allowing safe transfers on animals, cages and food between particular areas. In animal house about five thousands of mice in IVC system and about six thousands of mice in conventional cages, rats (about three thousands in IVC system) and rabbits may be kept at the same time including very sensitive immunodeficient strains of these animals commonly used in some specialized studies including transplantation and cancer research.

In experimental part well equipped surgery rooms are available. In this area several advanced instruments are localized. They include the computer tomography (Argus CT, Sedecal), in vivo visualization system (either fluorescence or luminescence readout – PhotonImager Optima Basic, Biospace Lab), X-ray machine (RS 2000X-R ay Biological Irradiator, RadSource) and equipment for behavioral experiments (IntelliCage by New Behavior and ActiMot2 System, TSE Systems). In other part of animal house there are three specialized laboratories. First is hematological and biochemical laboratory in which basic analyses of blood and urine components could be carried out. It is equipped also with two modern chromatographs working in both gas (GC – 2010 Plus, Shimadzu) and high performance liquid chromatography formats (HPLC Prominence, Shimadzu). Further, the histological laboratory equipped with several advanced machines allowing automatic processing of histological samples is located. Here the high quality microscope is installed as well. Third laboratory is equipped with the cell culture instrumentation including the CO2 incubator, sterile hood and inverted microscope. All analytical fields of animal house may be supported by very well equipped laboratories localized in biotechnology wing of WCAT.

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partners

Project is co-financed by the European Regional Development Fund under the Operational Programme Innovative Economy 2007-2013.